UniProt ID: F1QGR7 |
SUBCELLULAR LOCATION: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. SIMILARITY: Belongs to the RRM elav family. {ECO:0000256|ARBA:ARBA00006266, ECO:0000256|RuleBase:RU361281}. |
UniProt ID: A0A8M6Z808 |
SUBCELLULAR LOCATION: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. SIMILARITY: Belongs to the RRM elav family. {ECO:0000256|ARBA:ARBA00006266, ECO:0000256|RuleBase:RU361281}. |
UniProt ID: A0A8M9QIF9 |
SUBCELLULAR LOCATION: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. SIMILARITY: Belongs to the RRM elav family. {ECO:0000256|ARBA:ARBA00006266, ECO:0000256|RuleBase:RU361281}. |
UniProt ID: A0A8M9Q9I0 |
SUBCELLULAR LOCATION: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. SIMILARITY: Belongs to the RRM elav family. {ECO:0000256|ARBA:ARBA00006266, ECO:0000256|RuleBase:RU361281}. |
UniProt ID: A0A0R4IEW8 |
FUNCTION: RNA-binding protein that is involved in the post- transcriptional regulation of mRNAs (By similarity). Plays a role in the regulation of mRNA stability, alternative splicing and translation (By similarity). Binds to AU-rich element (ARE) sequences in the 3' untranslated region (3'UTR) of target mRNAs (By similarity). Mainly plays a role in neuron-specific RNA processing (By similarity). Required for the maturation of motor neuron axonal branches and dendrites (PubMed:29061699). {ECO:0000250|UniProtKB:P26378, ECO:0000250|UniProtKB:Q61701, ECO:0000269|PubMed:29061699}. SUBUNIT: Interacts with smn1. {ECO:0000269|PubMed:29061699}. SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O09032}. Perikaryon {ECO:0000250|UniProtKB:Q61701}. Cell projection, axon {ECO:0000250|UniProtKB:Q61701}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q61701}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q61701}. TISSUE SPECIFICITY: Expressed in motor neurons. {ECO:0000269|PubMed:29061699}. DISRUPTION PHENOTYPE: Reduced overall movement, decreased initiation of swim and turn movements and decreased mean body curvature change per swim half-cycle and mean number of swim half-cycles per swim (PubMed:29061699). At 2 and 4 dpf, decreased axonal branches and at 4 dpf, decreased dendrites in motor neurons (PubMed:29061699). Defects on motor neuron extensions persist at 26 dph (PubMed:29061699). Decreased GAP43 mRNA levels (PubMed:29061699). {ECO:0000269|PubMed:29061699}. SIMILARITY: Belongs to the RRM elav family. {ECO:0000255|RuleBase:RU361281}. SEQUENCE CAUTION: Sequence=AAA96940.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=AAH65965.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; |
UniProt ID: A0A8M2BEA7 |
SUBCELLULAR LOCATION: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. SIMILARITY: Belongs to the RRM elav family. {ECO:0000256|ARBA:ARBA00006266, ECO:0000256|RuleBase:RU361281}. |
UniProt ID: A0A8M9Q398 |
SUBCELLULAR LOCATION: Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}. SIMILARITY: Belongs to the RRM elav family. {ECO:0000256|ARBA:ARBA00006266, ECO:0000256|RuleBase:RU361281}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |