UniProt ID: O42363 |
FUNCTION: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). {ECO:0000250}. SUBUNIT: Homodimer (By similarity). Interacts with NAXE and YJEFN3 (PubMed:23719382). {ECO:0000250|UniProtKB:G5BQH5, ECO:0000269|PubMed:23719382}. SUBCELLULAR LOCATION: Secreted. DEVELOPMENTAL STAGE: Highly expressed in the yolk syncytial layer during embryonic (starting at the gastrula stage) and early larval development, an extraembryonic structure implicated in embryonic and larval nutrition. {ECO:0000269|PubMed:9238027}. SIMILARITY: Belongs to the apolipoprotein A1/A4/E family. {ECO:0000305}. SEQUENCE CAUTION: Sequence=AAH83473.1; Type=Frameshift; Evidence={ECO:0000305}; |
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