UniProt ID: Q90469 |
FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus. DEVELOPMENTAL STAGE: First expressed at 11 hours post-fertilization (hpf) in the dorsal presomitic mesoderm and neural keel at posterior levels, extending into the ventral somitic mesoderm during budding. At 22-26 hpf, expression decreases in the lateral and ventral mesoderm, but is maintained in the neural rod. Expression decreases from posterior to anterior with an anterior expression limit at somite 9. At 24-26 hpf, posterior expression begins to weaken and is undetectable by 40-56 hpf. {ECO:0000269|PubMed:8808402}. SIMILARITY: Belongs to the Abd-B homeobox family. {ECO:0000305}. |
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