UniProt ID: P47794 |
FUNCTION: Essential for the control of the cell cycle at the G1/S (start) transition. SUBUNIT: Interacts with CDK2 protein kinase to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. {ECO:0000250|UniProtKB:P24864}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P24864}. PTM: Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway. {ECO:0000250|UniProtKB:P24864}. SIMILARITY: Belongs to the cyclin family. Cyclin E subfamily. {ECO:0000305}. |
UniProt ID: B2GQF9 |
SIMILARITY: Belongs to the cyclin family. {ECO:0000256|RuleBase:RU000383}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |