UniProt ID: E7F1R5 |
FUNCTION: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. {ECO:0000256|ARBA:ARBA00003367, ECO:0000256|RuleBase:RU363085}. SUBUNIT: Component of a calcium channel complex consisting of a pore- forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2. {ECO:0000256|RuleBase:RU363085}. SUBCELLULAR LOCATION: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004415}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004415}. Membrane {ECO:0000256|RuleBase:RU363085}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU363085}. SIMILARITY: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. {ECO:0000256|ARBA:ARBA00007111, ECO:0000256|RuleBase:RU363085}. |
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