UniProt ID: E7F204
FUNCTION: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. {ECO:0000256|RuleBase:RU364016}.
CATALYTIC ACTIVITY: Reaction=an N-acetyl-beta-D-glucosaminyl derivative + UDP-N- acetyl-alpha-D-galactosamine = an N-acetyl-beta-D- galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP; Xref=Rhea:RHEA:20493, ChEBI:CHEBI:15378, ChEBI:CHEBI:58223, ChEBI:CHEBI:61631, ChEBI:CHEBI:67138, ChEBI:CHEBI:138027; EC=2.4.1.244; Evidence={ECO:0000256|RuleBase:RU364016};
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000256|RuleBase:RU364016}; Single-pass type II membrane protein {ECO:0000256|RuleBase:RU364016}.
SIMILARITY: Belongs to the chondroitin N- acetylgalactosaminyltransferase family. {ECO:0000256|RuleBase:RU364016}.
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