UniProt ID: B5L5I6 |
FUNCTION: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. {ECO:0000256|PIRNR:PIRNR036314}. SUBUNIT: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling. {ECO:0000256|PIRNR:PIRNR036314}. SIMILARITY: Belongs to the LDLR family. {ECO:0000256|PIRNR:PIRNR036314}. CAUTION: Lacks conserved residue(s) required for the propagation of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}. |
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