UniProt ID: A0A2R8Q3Q1 |
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000256|RuleBase:RU364149}. SUBUNIT: Component of the Mediator complex. {ECO:0000256|RuleBase:RU364149}. SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364149}. SIMILARITY: Belongs to the Mediator complex subunit 16 family. {ECO:0000256|ARBA:ARBA00006543, ECO:0000256|RuleBase:RU364149}. |
UniProt ID: E7F602 |
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000256|RuleBase:RU364149}. SUBUNIT: Component of the Mediator complex. {ECO:0000256|RuleBase:RU364149}. SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364149}. SIMILARITY: Belongs to the Mediator complex subunit 16 family. {ECO:0000256|ARBA:ARBA00006543, ECO:0000256|RuleBase:RU364149}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |