UniProt ID: B8JJK1 |
FUNCTION: Adenine glycosylase active on G-A mispairs. {ECO:0000256|RuleBase:RU365096}. CATALYTIC ACTIVITY: Reaction=Hydrolyzes free adenine bases from 7,8-dihydro-8- oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.; EC=3.2.2.31; Evidence={ECO:0000256|ARBA:ARBA00000843, ECO:0000256|RuleBase:RU365096}; COFACTOR: Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000256|RuleBase:RU365096}; Note=Binds 1 [4Fe-4S] cluster. {ECO:0000256|RuleBase:RU365096}; SIMILARITY: Belongs to the Nth/MutY family. {ECO:0000256|ARBA:ARBA00008343, ECO:0000256|RuleBase:RU365096}. |
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