UniProt ID: B8PYG1 |
FUNCTION: Stimulates outgrowth of olfactory axons and migration of hypophysiotropic gonadotropin-releasing hormone 3 (GnRH3) neurons. May couple NMDA-sensitive glutamate receptor signaling to the nucleus and trigger long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. {ECO:0000269|PubMed:19097186}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Nucleus envelope {ECO:0000250}. Nucleus membrane {ECO:0000250}. Nucleus matrix {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Synapse {ECO:0000250}. Synapse, synaptosome {ECO:0000250}. Postsynaptic density {ECO:0000250}. Membrane {ECO:0000250}. DEVELOPMENTAL STAGE: Expressed in the olfactory bulb, telencephalon, hypothalamus, midbrain tegmentum, retina, hindbrain and the spinal cord. Expressed in GnRH3 neurons within the olfactory epithelium and terminal nerve. {ECO:0000269|PubMed:19097186}. SIMILARITY: Belongs to the NSMF family. {ECO:0000305}. |
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