UniProt ID: F1QIB5 |
FUNCTION: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. {ECO:0000256|RuleBase:RU367014}. CATALYTIC ACTIVITY: Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; Evidence={ECO:0000256|ARBA:ARBA00001702}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670; Evidence={ECO:0000256|ARBA:ARBA00001702}; SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU367014}. Lysosome {ECO:0000256|RuleBase:RU367014}. SIMILARITY: Belongs to the GTR/RAG GTP-binding protein family. {ECO:0000256|ARBA:ARBA00007756, ECO:0000256|RuleBase:RU367014}. |
UniProt ID: A0A8M9PNV5 |
FUNCTION: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. {ECO:0000256|RuleBase:RU367014}. CATALYTIC ACTIVITY: Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; Evidence={ECO:0000256|ARBA:ARBA00001702}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670; Evidence={ECO:0000256|ARBA:ARBA00001702}; SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU367014}. Lysosome {ECO:0000256|RuleBase:RU367014}. SIMILARITY: Belongs to the GTR/RAG GTP-binding protein family. {ECO:0000256|ARBA:ARBA00007756, ECO:0000256|RuleBase:RU367014}. |
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