UniProt ID: A0A0R4IIB7 |
FUNCTION: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). {ECO:0000256|ARBA:ARBA00003743}. CATALYTIC ACTIVITY: Reaction=H2O + NAD(+) + succinate semialdehyde = 2 H(+) + NADH + succinate; Xref=Rhea:RHEA:13217, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30031, ChEBI:CHEBI:57540, ChEBI:CHEBI:57706, ChEBI:CHEBI:57945; EC=1.2.1.24; Evidence={ECO:0000256|RuleBase:RU365091}; PATHWAY: Amino-acid degradation; 4-aminobutanoate degradation. {ECO:0000256|ARBA:ARBA00005176, ECO:0000256|RuleBase:RU365091}. SUBUNIT: Homotetramer. {ECO:0000256|RuleBase:RU365091}. SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|RuleBase:RU365091}. SIMILARITY: Belongs to the aldehyde dehydrogenase family. {ECO:0000256|RuleBase:RU365091}. |
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