UniProt ID: A1L1G1 |
FUNCTION: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of fgfr2. Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of fgfr2 (By similarity). {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. SIMILARITY: Belongs to the ESRP family. {ECO:0000305}. |
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