UniProt ID: A0A8M6Z0Y8 |
CATALYTIC ACTIVITY: Reaction=Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76- residue protein attached to proteins as an intracellular targeting signal).; EC=3.4.19.12; Evidence={ECO:0000256|ARBA:ARBA00000707, ECO:0000256|RuleBase:RU366025}; SIMILARITY: Belongs to the peptidase C19 family. {ECO:0000256|RuleBase:RU366025}. |
UniProt ID: E7F6T8 |
FUNCTION: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of APC/C target proteins, thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex (By similarity). {ECO:0000250}. CATALYTIC ACTIVITY: Reaction=Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76- residue protein attached to proteins as an intracellular targeting signal).; EC=3.4.19.12; SIMILARITY: Belongs to the peptidase C19 family. {ECO:0000305}. |
UniProt ID: A0A8M3AVM6 |
CATALYTIC ACTIVITY: Reaction=Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76- residue protein attached to proteins as an intracellular targeting signal).; EC=3.4.19.12; Evidence={ECO:0000256|ARBA:ARBA00000707, ECO:0000256|RuleBase:RU366025}; SIMILARITY: Belongs to the peptidase C19 family. {ECO:0000256|RuleBase:RU366025}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |