UniProt ID: Q1JPT7
FUNCTION: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes (By similarity). {ECO:0000250}.
SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250}.
SIMILARITY: Belongs to the THAP1 family. {ECO:0000305}.
SEQUENCE CAUTION: Sequence=AAI16603.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin.; Evidence={ECO:0000305};
This information was provided by UniProt through a collaboration with ZFIN. (1)