FUNCTION: Plays a role in neuronal and neurobehavioral development (PubMed:31623237). Required for normal expression of neuronal markers elavl3 and eno2 and neurobehaviors related to circadian rhythm and changes in light-dark conditions (PubMed:31623237). {ECO:0000269|PubMed:31623237}. DEVELOPMENTAL STAGE: Highly expressed in the gut, myotomes and brain, especially the midbrain and hindbrain, at 3 days post-fertilization (dpf). {ECO:0000269|PubMed:31623237}. DISRUPTION PHENOTYPE: Double knockout of c3orf70a and c3orf70b resulted in significantly decreased expression of the mature neuron markers elavl3 and eno2 and the midbrain/hindbrain marker irx3b. Neurobehaviors related to circadian rhythm and altered light-dark conditions were significantly impaired. {ECO:0000269|PubMed:31623237}. SIMILARITY: Belongs to the UPF0524 family. {ECO:0000305}. |