UniProt ID: F8W5R6 |
FUNCTION: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA. {ECO:0000256|ARBA:ARBA00025629}. CATALYTIC ACTIVITY: Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112; EC=2.7.7.7; Evidence={ECO:0000256|ARBA:ARBA00024632}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|ARBA:ARBA00001946}; SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid {ECO:0000256|ARBA:ARBA00004436}. SIMILARITY: Belongs to the DNA polymerase type-A family. {ECO:0000256|ARBA:ARBA00007705}. |
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