UniProt ID: Q2N1D9 |
FUNCTION: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. {ECO:0000256|ARBA:ARBA00025493}. SUBUNIT: Interacts with FEM1A. {ECO:0000256|ARBA:ARBA00011094}. SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. SIMILARITY: Belongs to the G-protein coupled receptor 1 family. {ECO:0000256|RuleBase:RU000688}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |