UniProt ID: Q4KMJ1 |
FUNCTION: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. {ECO:0000250|UniProtKB:Q8WUX2}. CATALYTIC ACTIVITY: Reaction=glutathione = 5-oxo-L-proline + L-cysteinylglycine; Xref=Rhea:RHEA:47724, ChEBI:CHEBI:57925, ChEBI:CHEBI:58402, ChEBI:CHEBI:61694; EC=4.3.2.7; Evidence={ECO:0000250|UniProtKB:Q8WUX2}; SIMILARITY: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily. {ECO:0000305}. |
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