UniProt ID: Q2QKK0 |
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. |
UniProt ID: P60622 |
FUNCTION: Transcription regulator that modulates expression mediated by transcription factors of the GATA family. Cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context (By similarity). {ECO:0000250}. SUBUNIT: Interacts with the N-terminal zinc finger of gata1. {ECO:0000269|PubMed:14585986}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. TISSUE SPECIFICITY: Expressed at the lateral plate mesoderm. {ECO:0000269|PubMed:14585986}. DOMAIN: The CCHC FOG-type zinc fingers probably directly bind to GATA- type zinc fingers. The Tyr residue adjacent to the last Cys of the CCHC FOG-type zinc finger is probably essential for the interaction with GATA-type zinc fingers (By similarity). {ECO:0000250}. SIMILARITY: Belongs to the FOG (Friend of GATA) family. {ECO:0000255|PROSITE-ProRule:PRU01153}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |