UniProt ID: Q566T0 |
FUNCTION: Polycomb group (PcG) protein. Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). {ECO:0000250}. SUBUNIT: Component of the prc2/eed-ezh2 complex. {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. SIMILARITY: Belongs to the WD repeat ESC family. {ECO:0000305}. SEQUENCE CAUTION: Sequence=AAH93351.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
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