UniProt ID: A0A8M3AN93 |
SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. |
UniProt ID: A0A8M9PWK1 |
SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. |
UniProt ID: B2GQL1 |
SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. |
UniProt ID: A0A8M3AN88 |
SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. |
UniProt ID: Q58EK4 |
FUNCTION: Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of opa1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals. {ECO:0000250|UniProtKB:Q5XJY4}. CATALYTIC ACTIVITY: Reaction=Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.; EC=3.4.21.105; Evidence={ECO:0000250|UniProtKB:Q9H300}; SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9H300}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9H300}. SIMILARITY: Belongs to the peptidase S54 family. {ECO:0000255}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |