UniProt ID: A8E7G5
FUNCTION: Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). {ECO:0000250|UniProtKB:Q6P4A7, ECO:0000250|UniProtKB:Q9H9B4}.
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:24119684}; Multi-pass membrane protein {ECO:0000255}.
DISRUPTION PHENOTYPE: Morpholino knockdown of the protein causes erythroid abnormality and global defects in respiratory-chain activity. Morphant embryos exhibit erythrocytes with enlarged nuclei containing open chromatin, consistent with maturation arrest. The nuclear/cytoplasmic ratio is increased nearly 3-fold. Anemia cannot be rescued neither by exogenous folate or vitamin B12 supplementation, nor by N-acetylcysteine treatment. {ECO:0000269|PubMed:24119684}.
SIMILARITY: Belongs to the sideroflexin family. {ECO:0000305}.
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