UniProt ID: Q6P949
FUNCTION: Lysine demethylase that demethylates both histones and non-histone proteins. Mediates demethylation of dimethylated 'Lys- 9' of histone H3 (H3K9me2). Recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA (By similarity). {ECO:0000250}.
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:O75151}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:O75151}.
SIMILARITY: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily. {ECO:0000305}.
SEQUENCE CAUTION: Sequence=AAH60927.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
UniProt ID: F6NB59
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS01092803}.
UniProt ID: F1Q721
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS01092803}.
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