UniProt ID: Q5EAQ1 |
FUNCTION: Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation (By similarity). {ECO:0000250}. SUBUNIT: Interacts with eif4g1, eif4g2 and slbp; probably tethered by SLBP to the 3'-end of mRNAs ending with the histone stem-loop, it also interacts with eif4g1 which is bound to their 5'-end. {ECO:0000250}. INTERACTION: Q5EAQ1; Q7ZU28: ddx19b; NbExp=2; IntAct=EBI-16419713, EBI-16419754; Q5EAQ1; Q5EAQ1: mif4gdb; NbExp=2; IntAct=EBI-16419713, EBI-16419713; SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. SIMILARITY: Belongs to the MIF4GD family. {ECO:0000305}. |
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