UniProt ID: Q5U379 |
FUNCTION: Involved in chromatin-remodeling. Core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity). {ECO:0000250|UniProtKB:Q12824}. SUBUNIT: Component of the multiprotein chromatin-remodeling complexes SWI/SNF. Component of neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) (By similarity). Component of the BAF (SWI/SNF) chromatin remodeling complex. Component of the SWI/SNF-B (PBAF) chromatin remodeling complex. Binds to double-stranded DNA (By similarity). {ECO:0000250|UniProtKB:Q12824, ECO:0000250|UniProtKB:Q9Z0H3}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. DOMAIN: The N-terminal DNA-binding region is structurally similar to winged helix domains. {ECO:0000250|UniProtKB:Q12824}. SIMILARITY: Belongs to the SNF5 family. {ECO:0000305}. |
UniProt ID: A8WG87 |
SUBUNIT: Component of the multiprotein chromatin-remodeling complexes SWI/SNF. {ECO:0000256|PIRNR:PIRNR038126}. SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR038126}. SIMILARITY: Belongs to the SNF5 family. {ECO:0000256|ARBA:ARBA00010239, ECO:0000256|PIRNR:PIRNR038126}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |