UniProt ID: Q5U398 |
FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. {ECO:0000256|PIRNR:PIRNR037201}. CATALYTIC ACTIVITY: Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L- cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.; EC=2.3.2.26; Evidence={ECO:0000256|PIRNR:PIRNR037201}; PATHWAY: Protein modification; protein ubiquitination. {ECO:0000256|PIRNR:PIRNR037201}. SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR037201}. Nucleus {ECO:0000256|PIRNR:PIRNR037201}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |