UniProt ID: Q5XLR4 |
FUNCTION: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity). {ECO:0000250}. SUBUNIT: Component of the CPC complex. {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. {ECO:0000250}. SIMILARITY: Belongs to the borealin family. {ECO:0000305}. |
UniProt ID: B2GQ71 |
SUBCELLULAR LOCATION: Chromosome, centromere {ECO:0000256|ARBA:ARBA00004584}. SIMILARITY: Belongs to the borealin family. {ECO:0000256|ARBA:ARBA00009914}. |
UniProt ID: F1RBV2 |
SUBCELLULAR LOCATION: Chromosome, centromere {ECO:0000256|ARBA:ARBA00004584}. SIMILARITY: Belongs to the borealin family. {ECO:0000256|ARBA:ARBA00009914}. |
UniProt ID: A0A8M6YUH5 |
SUBCELLULAR LOCATION: Chromosome, centromere {ECO:0000256|ARBA:ARBA00004584}. SIMILARITY: Belongs to the borealin family. {ECO:0000256|ARBA:ARBA00009914}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |