UniProt ID: F1REK1 |
FUNCTION: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. {ECO:0000256|ARBA:ARBA00025219, ECO:0000256|PIRNR:PIRNR001152}. SUBUNIT: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity. {ECO:0000256|ARBA:ARBA00025867}. SIMILARITY: Belongs to the peptidase S1 family. Plasminogen subfamily. {ECO:0000256|PIRNR:PIRNR001152}. CAUTION: Lacks conserved residue(s) required for the propagation of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00121}. |
UniProt ID: Q5RGG3 |
FUNCTION: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. {ECO:0000256|ARBA:ARBA00025219, ECO:0000256|PIRNR:PIRNR001152}. SUBUNIT: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity. {ECO:0000256|ARBA:ARBA00025867}. SIMILARITY: Belongs to the peptidase S1 family. Plasminogen subfamily. {ECO:0000256|PIRNR:PIRNR001152}. CAUTION: Lacks conserved residue(s) required for the propagation of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00121}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |