UniProt ID: F1QC17 |
FUNCTION: May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. {ECO:0000250|UniProtKB:Q9Y6C2}. SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q9Y6C2}. DISRUPTION PHENOTYPE: Morphants at 48 hpf display body curvature defects, impaired brain development, and motor neuron defects with abnormal development of axons and decreased arborization. Morphant embryos and larvae have decreased locomotor activity compared to wild- type. {ECO:0000269|PubMed:31978608}. |
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