UniProt ID: Q66L51 |
FUNCTION: Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). {ECO:0000255|HAMAP-Rule:MF_03191}. CATALYTIC ACTIVITY: Reaction=a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S- adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl- 1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:28286, Rhea:RHEA-COMP:10858, Rhea:RHEA-COMP:10859, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:84166, ChEBI:CHEBI:84167; EC=2.1.1.201; Evidence={ECO:0000255|HAMAP-Rule:MF_03191}; PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03191}. SUBUNIT: Component of a multi-subunit COQ enzyme complex, composed of at least coq3, coq4, coq5, coq6, coq7 and coq9. {ECO:0000255|HAMAP- Rule:MF_03191}. SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000255|HAMAP- Rule:MF_03191}; Peripheral membrane protein {ECO:0000255|HAMAP- Rule:MF_03191}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03191}. SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. {ECO:0000255|HAMAP-Rule:MF_03191}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |