UniProt ID: Q6DBX1 |
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). {ECO:0000250}. SUBUNIT: Component of the Mediator complex. {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus {ECO:0000305}. SIMILARITY: Belongs to the Mediator complex subunit 20 family. {ECO:0000305}. SEQUENCE CAUTION: Sequence=CAK03596.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
UniProt ID: A0A8M3AMM6 |
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000256|ARBA:ARBA00025687, ECO:0000256|RuleBase:RU364152}. SUBUNIT: Component of the Mediator complex. {ECO:0000256|RuleBase:RU364152}. SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU364152}. SIMILARITY: Belongs to the Mediator complex subunit 20 family. {ECO:0000256|ARBA:ARBA00010743, ECO:0000256|RuleBase:RU364152}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |