UniProt ID: Q5SPD5 |
FUNCTION: Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. {ECO:0000256|ARBA:ARBA00002870}. PATHWAY: Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2. {ECO:0000256|ARBA:ARBA00004883}. SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. {ECO:0000256|ARBA:ARBA00005959}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |