UniProt ID: Q6DG03 |
FUNCTION: Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53- dependent growth arrest. Binds to the consensus sequence 5'- CCCG[GT]ATGT-3'. {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}. SIMILARITY: Belongs to the DMTF1 family. {ECO:0000305}. |
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