UniProt ID: A0A0R4II16 |
FUNCTION: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. {ECO:0000256|ARBA:ARBA00024805}. SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}. SIMILARITY: Belongs to the proteasome inhibitor PI31 family. {ECO:0000256|ARBA:ARBA00006405}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |