UniProt ID: Q6IQ63
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). {ECO:0000250}.
SUBUNIT: Component of the Mediator complex. {ECO:0000250}.
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
SIMILARITY: Belongs to the Mediator complex subunit 6 family. {ECO:0000305}.
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