UniProt ID: Q6IQR8 |
CATALYTIC ACTIVITY: Reaction=diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine; Xref=Rhea:RHEA:17973, ChEBI:CHEBI:17368, ChEBI:CHEBI:33019, ChEBI:CHEBI:58017, ChEBI:CHEBI:58053; EC=2.4.2.8; Evidence={ECO:0000256|RuleBase:RU364099}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|RuleBase:RU364099}; PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1. {ECO:0000256|RuleBase:RU364099}. SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU364099}. SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase family. {ECO:0000256|ARBA:ARBA00008391, ECO:0000256|RuleBase:RU364099}. |
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