UniProt ID: Q6IQM5 |
FUNCTION: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. {ECO:0000256|ARBA:ARBA00025463}. PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis. {ECO:0000256|ARBA:ARBA00004687}. SUBUNIT: Forms a complex with PIGT, PIGS, PIGU and GAA1. {ECO:0000256|ARBA:ARBA00011178}. SIMILARITY: Belongs to the peptidase C13 family. {ECO:0000256|ARBA:ARBA00009941}. |
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