UniProt ID: Q7ZUX3 |
FUNCTION: Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation (By similarity). Binds phosphatidylinositol 3-phosphate (PtdIns3P) (By similarity). {ECO:0000250|UniProtKB:Q9Y484}. SUBCELLULAR LOCATION: Preautophagosomal structure {ECO:0000250|UniProtKB:Q9Y484}. DOMAIN: The L/FRRG motif is required for recruitment to PtdIns3P. {ECO:0000250|UniProtKB:Q9Y4P8}. SIMILARITY: Belongs to the WD repeat PROPPIN family. {ECO:0000305}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |