UniProt ID: F1RAE2 |
FUNCTION: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. {ECO:0000256|RuleBase:RU364004}. SUBUNIT: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs). {ECO:0000256|RuleBase:RU364004}. SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|RuleBase:RU364004}. SIMILARITY: Belongs to the GAR1 family. {ECO:0000256|RuleBase:RU364004}. |
UniProt ID: Q7ZVE0 |
FUNCTION: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). {ECO:0000250}. SUBUNIT: Component of the small nucleolar ribonucleoprotein particle containing H/ACA-type snoRNAs (H/ACA snoRNPs) (By similarity). Component of the telomerase holoenzyme complex (By similarity). {ECO:0000250|UniProtKB:Q9NY12}. SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}. SIMILARITY: Belongs to the GAR1 family. {ECO:0000305}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |