UniProt ID: A0A8M1P4I3 |
FUNCTION: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. {ECO:0000256|RuleBase:RU367034}. SUBUNIT: Binds actin and the Arp2/3 complex. {ECO:0000256|RuleBase:RU367034}. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU367034}. SIMILARITY: Belongs to the SCAR/WAVE family. {ECO:0000256|ARBA:ARBA00006993, ECO:0000256|RuleBase:RU367034}. |
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