UniProt ID: Q6NUX4 |
CATALYTIC ACTIVITY: Reaction=H2O + leukotriene A4 = leukotriene B4; Xref=Rhea:RHEA:22324, ChEBI:CHEBI:15377, ChEBI:CHEBI:57461, ChEBI:CHEBI:57463; EC=3.3.2.6; Evidence={ECO:0000256|RuleBase:RU361141}; COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000256|PIRSR:PIRSR612777-3, ECO:0000256|RuleBase:RU361141}; Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR612777-3, ECO:0000256|RuleBase:RU361141}; PATHWAY: Lipid metabolism; leukotriene B4 biosynthesis. {ECO:0000256|ARBA:ARBA00004716, ECO:0000256|RuleBase:RU361141}. SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU361141}. SIMILARITY: Belongs to the peptidase M1 family. {ECO:0000256|ARBA:ARBA00010136, ECO:0000256|RuleBase:RU361141}. |
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