UniProt ID: A9JT50 |
SIMILARITY: Belongs to the DDA1 family. {ECO:0000256|ARBA:ARBA00008042}. |
UniProt ID: Q7T2A3 |
FUNCTION: Functions as a component of numerous distinct DCX (DDB1-CUL4- X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex. {ECO:0000250|UniProtKB:Q9BW61}. PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:Q9BW61}. SUBUNIT: Component of numerous DCX (DDB1-CUL4-X-box) E3 ubiquitin- protein ligase complexes which consist of a core of DDB1, cullin-4 (CUL4A or CUL4B), DDA1 and RBX1. {ECO:0000250|UniProtKB:Q9BW61}. SIMILARITY: Belongs to the DDA1 family. {ECO:0000305}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |