UniProt ID: Q7SXM7 |
FUNCTION: Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. {ECO:0000250|UniProtKB:Q8WWY3}. SUBUNIT: Identified in the spliceosome B complex. Component of the U4/U6-U5 tri-snRNP complex. Component of some MLL1/MLL complex. {ECO:0000250|UniProtKB:Q8WWY3}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8WWY3}. Nucleus speckle {ECO:0000250|UniProtKB:Q8WWY3}. Nucleus, Cajal body {ECO:0000250|UniProtKB:Q8WWY3}. Note=Predominantly found in speckles and in Cajal bodies. {ECO:0000250|UniProtKB:Q8WWY3}. DOMAIN: Interacts with the snRNP via the Nop domain. {ECO:0000250|UniProtKB:Q8WWY3}. DOMAIN: The coiled coil domain is formed by two non-contiguous helices. {ECO:0000250|UniProtKB:Q8WWY3}. SIMILARITY: Belongs to the PRP31 family. {ECO:0000305}. |
UniProt ID: B2GS36 |
SUBCELLULAR LOCATION: Nucleus, Cajal body {ECO:0000256|ARBA:ARBA00004408}. SIMILARITY: Belongs to the PRP31 family. {ECO:0000256|ARBA:ARBA00005572}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |