UniProt ID: Q5XJ85
FUNCTION: Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. {ECO:0000269|PubMed:16552074}.
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
DEVELOPMENTAL STAGE: Expression is highest in adults. In the embryo, maternal transcript levels are reduced during blastula and gastrula stages. Expression increases during segmentation and later stages. {ECO:0000269|PubMed:16552074}.
DOMAIN: The intermediate domain (ID) is required for the phosphorylation and activation of IRAK. {ECO:0000250}.
UniProt ID: A0A0R4I9A6
FUNCTION: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. {ECO:0000256|PIRNR:PIRNR037756}.
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR037756}.
UniProt ID: B2GQ86
FUNCTION: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. {ECO:0000256|PIRNR:PIRNR037756}.
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR037756}.
This information was provided by UniProt through a collaboration with ZFIN. (1)