UniProt ID: F1QZJ9 |
SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. SIMILARITY: Belongs to the DoxX family. {ECO:0000256|ARBA:ARBA00006679}. |
UniProt ID: Q58EL2 |
FUNCTION: Molecular chaperone which mediates the proper assembly and functional expression of the nicotinic acetylcholine receptors (nAChRs) throughout the brain (By similarity). Essential for the proper folding, assembly, function and surface trafficking of alpha-7 (CHRNA7), alpha- 4-beta-2, alpha-3-beta-2 and alpha-3-beta-4 receptors (By similarity). {ECO:0000250|UniProtKB:Q53FP2}. SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250|UniProtKB:Q9D328}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q6JAM9}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9D328}; Multi- pass membrane protein {ECO:0000255}. Note=Shedding may lead to a soluble peptide. {ECO:0000250|UniProtKB:Q6JAM9}. SIMILARITY: Belongs to the DoxX family. {ECO:0000305}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |