UniProt ID: Q7ZTZ3
FUNCTION: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. {ECO:0000256|RuleBase:RU361118}.
CATALYTIC ACTIVITY: Reaction=alpha-D-mannose 1-phosphate = D-mannose 6-phosphate; Xref=Rhea:RHEA:11140, ChEBI:CHEBI:58409, ChEBI:CHEBI:58735; EC=5.4.2.8; Evidence={ECO:0000256|RuleBase:RU361118};
PATHWAY: Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6- phosphate: step 2/2. {ECO:0000256|RuleBase:RU361118}.
SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU361118}.
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU361118}.
SIMILARITY: Belongs to the eukaryotic PMM family. {ECO:0000256|RuleBase:RU361118}.
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