UniProt ID: Q7ZZU7 |
FUNCTION: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. {ECO:0000256|ARBA:ARBA00002007}. SUBUNIT: Homodimer; disulfide-linked. {ECO:0000256|PIRNR:PIRNR001787}. SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}. SIMILARITY: Belongs to the TGF-beta family. {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|PIRNR:PIRNR001787, ECO:0000256|RuleBase:RU000354}. |
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