UniProt ID: Q5W8I8
FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. Required for glutamate release by retinotectal synapses and visual acuity. {ECO:0000269|PubMed:17196531}.
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell junction, synapse, synaptosome {ECO:0000250}.
TISSUE SPECIFICITY: Expressed in spinal chord and retinal ganglion cells. {ECO:0000269|PubMed:15515020, ECO:0000269|PubMed:17196531, ECO:0000269|PubMed:17941721}.
SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. {ECO:0000305}.
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