UniProt ID: Q90Z08
FUNCTION: Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N- terminally myristoylated proteins and is required for their localization. Plays a key role in localization of proteins to the primary cilium membrane. {ECO:0000269|PubMed:22085962}.
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000250}.
TISSUE SPECIFICITY: Detected in embryo. Detected in larvae four days after fertilization, in retina and neural tissues (at protein level). Detected in embryos at the sphere stage, during gastrulation, somitogenesis and in swimming larvae, both within and outside of the developing nervous system. Detected in adults. {ECO:0000269|PubMed:15593328}.
DOMAIN: Adopts an immunoglobulin-like beta-sandwich fold forming a hydrophobic cavity that capture N-terminally myristoylated target peptides. Phe residues within the hydrophobic beta sandwich are required for myristate binding (By similarity). {ECO:0000250}.
SIMILARITY: Belongs to the PDE6D/unc-119 family. {ECO:0000305}.
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